Adverse Effects of Oral Acne MedicinesOral acne drugs treat the condition from within your body by reducing hormones that boost oil manufacturing. These include anti-biotics such as tetracycline (Tetracin, Tetracap) and minocycline (Solodyn, Minocin) and the pill called spironolactone (Aldactone).Some dental drugs are available over-the-counter whi